Focused Ultrasonicator Instrument Powers Accurate Sample Prep

Precision in sample preparation is no longer just a luxury – it’s a necessity. For researchers and scientists navigating the demands of modern genomics, inconsistency in sample prep can mean flawed data, wasted time, and lost funding. That’s why more labs are turning to one key innovation: the Focused Ultrasonicator Instrument. At Longlight Technology, we’ve developed the BoFU-100 – a focused ultrasonicator system designed to simplify complex workflows while dramatically improving sample accuracy and repeatability. Whether you’re working with delicate tissue samples or fragmenting DNA for sequencing, the BoFU-100 offers a dependable solution grounded in precision.

The Focused Ultrasonicator Instrument BoFU-100 is tailored for both clinical diagnostics and scientific research applications. In hospitals and clinical laboratories – such as departments of pathology and laboratory medicine – it is ideal for deparaffinization of FFPE tissue samples, DNA extraction from tumor tissues, and lysis of liquid biopsy specimens, supporting precision diagnostics and molecular pathology workflows. In universities and research institutes, the BoFU-100 serves as a core tool in molecular biology, genomics, and epigenetics labs. Common users like graduate students and lab technicians rely on it for high-efficiency DNA shearing prior to NGS library preparation, as well as chromatin fragmentation for ChIP-seq and related applications. With precise control, high reproducibility, and user-friendly operation, BoFU-100 bridges clinical and research needs in nucleic acid preparation.

Why Sample Prep Accuracy Matters More Than Ever

Every seasoned scientist knows: poor sample prep leads to poor results. Manual errors, uneven energy delivery, and temperature fluctuations can throw off even the best-planned experiments. In genomic workflows like NGS, ChIP-seq, or RNA extraction, even minor inconsistencies in fragment size or yield can impact downstream data quality.

That’s where the Focused Ultrasonicator Instrument comes in. Instead of relying on outdated sonic bath systems or imprecise probe-based disruption, the BoFU-100 uses confocal ultrasound technology to focus high-frequency, short-wavelength energy directly on the sample. The result? A highly controlled environment where every variable – from energy intensity to temperature – is regulated in real-time.

And here’s the real game-changer: the BoFU-100 operates without direct contact. The sample remains completely untouched by probes or physical parts, reducing the risk of cross-contamination and preserving the biological integrity of even your most valuable materials.

What Makes the BoFU-100 Stand Out

Let’s be honest – lab equipment tends to overpromise and underdeliver. That’s why we built the BoFU-100 with practicality at its core. It’s not just precise; it’s user-friendly, quiet, compact, and adaptable to real-world lab conditions. We designed it for researchers who don’t have time to babysit their equipment or troubleshoot for hours.

Some standout features of the BoFU-100 include:

✅ Non-contact sample processing – Reduces contamination risk and preserves sample integrity

✅ Advanced temperature control – True low-temperature and constant-temperature processing with built-in sensors

✅ Plug-and-play operation – No external computers or refrigeration systems required

✅ Quiet and compact – Operates silently without the need for bulky sound insulation

One of our design priorities was ease of use. With BoFU-100, all you need to do is place your sample, enter a few parameters, and press start. The internal system handles the rest, ensuring consistent results without complicated steps or repeated calibration. We know lab space is always at a premium. That’s why our ultrasonicator’s integrated design eliminates the need for external modules, saving you both space and setup time.

Real-World Applications Across Research Fields

You may be wondering: where exactly does a Focused Ultrasonicator Instrument fit in your workflow? The answer is – almost anywhere. From academic labs to clinical diagnostics and biopharmaceutical R&D, the BoFU-100 has a place in any setting that requires precise and efficient sample disruption.

Here are just a few ways researchers are using the BoFU-100 today:

✅ DNA, RNA, and chromatin shearing for NGS or ChIP-seq applications

✅ Deparaffinization of FFPE samples for pathology or retrospective studies

✅ Cell and tissue lysis for protein or genome extraction

✅ Homogenization of biological fluids or tissues for downstream analysis

✅ Fragmentation of genomic material for sequencing prep

In each of these scenarios, the focused energy and accurate temperature control help preserve nucleic acid quality, improve yields, and reduce variability between samples. Our clients often tell us that switching to a Focused Ultrasonicator Instrument has eliminated common prep issues – like inconsistent fragment sizes or overheated samples – that previously led to failed sequencing runs.

About Longlight Technology

We’re not just another lab equipment manufacturer. At Longlight Technology, we’re scientists, too. We understand the everyday challenges of research and the frustration of working with tools that don’t meet expectations.

That’s why we built the BoFU-100 from the ground up – combining innovative ultrasound engineering with deep industry knowledge. Beyond ultrasonication, we also provide a full suite of genomics tools, including:

• Precast agarose gels for electrophoresis

• Nucleic acid extraction kits

• Library prep kits for NGS

• Nucleic acid scavengers

• Qubit-compatible assay tubes

Our mission is simple: to help you do better science. From basic research to advanced molecular diagnostics, we support innovation with dependable tools and personal support. We’re especially proud to contribute to the growth of precision medicine and genomic discovery.

Final Words

Science is advancing faster than ever – but sample prep is still one of the most time-consuming steps in many workflows. If you’re tired of wasting time repeating experiments or troubleshooting poor results, it may be time to upgrade your tools. The Focused Ultrasonicator Instrument isn’t just a piece of equipment. It’s a smarter, more reliable way to work. With BoFU-100, you can stop worrying about variability and focus on what really matters – your data.

Ready to experience precision without compromise?

Contact us at Longlight Technology to learn more about how the BoFU-100 Focused Ultrasonicator Instrument can transform your lab’s efficiency and confidence in every prep.